TNFRSF1A

TNFRSF1A
TNFRSF1A
	1EXT
Доступные структуры
PDB	Поиск ортологов: PDBe, RCSB
	Список идентификаторов PDB 1EXT, 1FT4, 1ICH, 1NCF, 1TNR
Идентификаторы
Символ	TNFRSF1A ; CD120a; FPF; MS5; TBP1; TNF-R; TNF-R-I; TNF-R55; TNFAR; TNFR1; TNFR1-d2; TNFR55; TNFR60; p55; p55-R; p60
Внешние ID	OMIM: 191190 MGI: 1314884 HomoloGene: 828 ChEMBL: 3378 GeneCards: Ген TNFRSF1A
Функция	• protease binding; • tumor necrosis factor-activated receptor activity; • protein binding; • protein complex binding; • tumor necrosis factor binding;
Компонент клетки	• Golgi membrane; • extracellular region; • extracellular space; • nucleus; • plasma membrane; • integral component of plasma membrane; • cell surface; • axon; • receptor complex; • membrane raft;
Биологический процесс	• response to hypoxia; • prostaglandin metabolic process; • apoptotic process; • inflammatory response; • extrinsic apoptotic signaling pathway via death domain receptors; • intrinsic apoptotic signaling pathway in response to DNA damage; • negative regulation of gene expression; • viral process; • cytokine-mediated signaling pathway; • response to lipopolysaccharide; • negative regulation of interleukin-6 production; • positive regulation of tumor necrosis factor production; • tetrapyrrole metabolic process; • positive regulation of protein import into nucleus, translocation; • tumor necrosis factor-mediated signaling pathway; • positive regulation of tyrosine phosphorylation of Stat1 protein; • defense response to bacterium; • negative regulation of apoptotic process; • positive regulation of I-kappaB kinase/NF-kappaB signaling; • response to amino acid; • response to alkaloid; • response to ethanol; • positive regulation of angiogenesis; • positive regulation of transcription from RNA polymerase II promoter; • negative regulation of inflammatory response; • positive regulation of inflammatory response; • protein heterooligomerization; • cellular response to mechanical stimulus; • cellular response to estradiol stimulus; • apoptotic signaling pathway;
	Источники: Amigo / QuickGO
Профиль экспрессии РНК
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Ортологи

TNFRSF1A (англ. tumor necrosis factor receptor superfamily, member 1A) — мембранный белок, рецептор из надсемейства рецепторов фактора некроза опухоли. У человека кодируется геном TNFRSF1A.